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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FECH
All Species:
32.73
Human Site:
S130
Identified Species:
55.38
UniProt:
P22830
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22830
NP_000131.2
423
47862
S130
Y
R
R
I
G
G
G
S
P
I
K
I
W
T
S
Chimpanzee
Pan troglodytes
Q3YA36
423
47946
S130
Y
R
R
I
G
G
G
S
P
I
K
I
W
T
S
Rhesus Macaque
Macaca mulatta
XP_001085580
422
47841
S129
Y
R
R
I
G
G
G
S
P
I
K
I
W
T
S
Dog
Lupus familis
XP_852936
400
45170
K115
P
I
K
M
W
T
S
K
Q
G
E
G
M
V
K
Cat
Felis silvestris
Mouse
Mus musculus
P22315
420
47112
S127
E
R
R
I
G
G
G
S
P
I
K
M
W
T
S
Rat
Rattus norvegicus
NP_001101904
422
47533
S129
Y
R
R
I
G
G
G
S
P
I
K
M
W
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510557
430
49042
S137
Y
S
R
I
G
G
G
S
P
I
K
M
W
T
T
Chicken
Gallus gallus
O42479
402
45411
K113
G
G
G
S
P
I
K
K
W
T
A
V
Q
G
E
Frog
Xenopus laevis
O57478
411
46021
S117
Y
S
K
I
G
G
G
S
P
I
K
K
W
T
E
Zebra Danio
Brachydanio rerio
NP_571706
409
46017
S116
Y
S
K
I
G
G
G
S
P
I
K
A
W
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9S8
384
43579
E113
Q
L
D
R
I
S
P
E
T
A
P
H
K
H
Y
Honey Bee
Apis mellifera
XP_393413
397
45521
C117
N
K
Q
G
K
L
L
C
E
K
L
D
K
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04921
512
56600
S167
Y
A
S
I
G
G
G
S
P
L
R
H
I
T
D
Baker's Yeast
Sacchar. cerevisiae
P16622
393
44578
E114
W
S
E
Y
Q
A
T
E
V
C
K
I
L
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
86
N.A.
88.1
88.8
N.A.
82.7
79.6
78.4
71.8
N.A.
49.1
48.2
N.A.
N.A.
Protein Similarity:
100
99
96.9
89.5
N.A.
92.6
93.1
N.A.
89.3
85.1
85.3
81.8
N.A.
64.7
66.4
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
93.3
N.A.
80
0
73.3
73.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
100
N.A.
93.3
6.6
80
86.6
N.A.
0
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.2
45.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
8
0
8
0
0
0
0
15
8
0
8
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
8
65
65
65
0
0
8
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
8
0
% H
% Ile:
0
8
0
65
8
8
0
0
0
58
0
29
8
8
0
% I
% Lys:
0
8
22
0
8
0
8
15
0
8
65
8
15
0
15
% K
% Leu:
0
8
0
0
0
8
8
0
0
8
8
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
22
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
8
0
65
0
8
0
0
0
0
% P
% Gln:
8
0
8
0
8
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
36
43
8
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
29
8
8
0
8
8
65
0
0
0
0
0
0
43
% S
% Thr:
0
0
0
0
0
8
8
0
8
8
0
0
0
65
15
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% V
% Trp:
8
0
0
0
8
0
0
0
8
0
0
0
58
0
0
% W
% Tyr:
58
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _